A2M IN BONE CANCER (ISSN 2753-8176 (online)) - brief report
A2M IN BONE CANCER (ISSN 2753-8176 (online)) - brief report 1.Ana Pedro 1.Gwyntwr1386 Health & Social Care, 58 Grove Rd, Birkenhead, CH42 3XX. info@gwyntwr1386.com Osteosarcoma is a type of bone sarcoma or primary bone cancer which usually develops in growing bones and can affect any bone although most common areas are the arms or legs. It is most often found in teenagers and young adults, although it can happen at any age. Around 1 in 10 osteosarcomas (10%) develop in adults in their 60s and 70s (1). Ewing tumors, however can start in either the bone or the soft tissue (2). Here, we analyzed by proteomics analysis, the content of the precipitates derived from the ultracentrifugation of conditioned media derived from the cell culture of different bone cancer cell lines (table 1). We found out that A2M is present in all cancer cell lines types with significant scores and that is present in higher levels in the osteosarcoma cell line 143B rather than in Ewing’s sarcoma cell lin...