Does A2M predicts cancer appearance or progression in skin? (ISSN 2753-8176 (online))
Does A2M predicts cancer appearance or progression in skin? (ISSN 2753-8176 (online)) 1.Ana Pedro 1.Gwyntwr1386 Health & Social Care, Harold Tomlin Day Centre, 24 Grosvenor Street, Chester, CH1 2DD. info@gwyntwr1386.com Introduction In our previous article we analyzed the hypothesis that A2M predicts cancer appearance or progression in the breast (1), now we analyse if this hypothesis might be true as well in the case of the skin. The interstitial fluid and the deriving lymph are in direct contact with the cellular layer of each organ. Therefore, the analysis of the composition of the lymphatic fluid (LF) may provide precise pathological biochemical and cellular information about an organ including the skin (2). For these reasons, we collected LF samples both from healthy patients and cutaneous melanoma (CM) patients suffering from different stages of the disease, and submitted these samples to proteomic analysis and analyzed the expression of A2M in these sa...