Gwyntwr1386 Science Journal

A2M function in pancreatic cancer in mouse (ISSN 2753-8176 (online)) 1.Ana Pedro 1.Gwyntwr1386 Health & Social Care, Harold Tomlin Day Centre, 24 Grosvenor Street, Chester, CH1 2DD. info@gwyntwr1386.com Introduction, results and discussion In our previous article we analyzed the hypothesis that A2M predicts cancer appearance or progression in the breast (1) and in the skin (2), now we analyse if this hypothesis might be true as well in the case of pancreatic cancer in mouse. The most common type of pancreatic cancer (PC) is adenocarcinoma, which accounts for 90% of the cases. Around 1-2% of the PC cases have a neuroendocrine origin, arising from the hormone-producing cells of the pancreas being in general less aggressive than the adenocarcinoma (3). In table 1, we found Mascot scores for two different mouse normal pancreas tissue CM samples (one shows a significant Mascot Score, while the other shows no A2M), PanIn cell ...

Does A2M predicts cancer appearance or progression in skin? (ISSN 2753-8176 (online)) 1.Ana Pedro 1.Gwyntwr1386 Health & Social Care, Harold Tomlin Day Centre, 24 Grosvenor Street, Chester, CH1 2DD. info@gwyntwr1386.com Introduction In our previous article we analyzed the hypothesis that A2M predicts cancer appearance or progression in the breast (1), now we analyse if this hypothesis might be true as well in the case of the skin. The interstitial fluid and the deriving lymph are in direct contact with the cellular layer of each organ. Therefore, the analysis of the composition of the lymphatic fluid (LF) may provide precise pathological biochemical and cellular information about an organ including the skin (2). For these reasons, we collected LF samples both from healthy patients and cutaneous melanoma (CM) patients suffering from different stages of the disease, and submitted these samples to proteomic analysis and analyzed the expression of A2M in these sa...