Does Alpha-2-macroglobulin (α2M) predicts breast cancer development or progression? (ISSN 2753-8176 (online))
Does Alpha-2-macroglobulin (α2M) predicts breast cancer development or progression? (ISSN 2753-8176 (online)) 1. Ana Pedro 1.Gwyntwr1386 Health & Social Care, Harold Tomlin Day Centre, 24 Grosvenor Street, Chester, CH1 2DD, info@gwyntwr1386.com Introduction, Results and Discussion Alpha-2-macroglobulin (α2M) is a large protein found in the blood which is mainly produced by the liver. α2M is the largest major non-immunoglobulin protein in human plasma (1). It functions as a broad-spectrum protease inhibitor which are involved in various biological processes such as inflammation, cell growth, and blood clotting (2). α2M can also bind to and regulate cytokines and growth factors, thus influencing the immune system response (3). α2M also may play a role in various cancers and has been implicated in the development of some cancers and also as a tumor suppressor in other cancer types (4). α2M may act as an anticancer agent by inhibiting proteases, which are enzymes that can...