Gwyntwr1386 Science Journal

Ana Pedro 1 1 Gwyntwr1386 Healthcare CIC, Regus Chester Business Park, Heronsway, Chester, CH49QR, UK Keywords: ASD, APOE, APOL1 1. Corresponding author: anapedrolaboratories@gmail.com Autism spectrum disorder (ASD) are a group of developmental disabilities which cause impairments in social skills, communication and repetitive behaviours. This causes big obstacles in interpersonal relationships and it is a heavy burden for society and the families of autistic individuals (1) We performed FunRich analysis (http://www.funrich.org/) of proteomics data derived from plasma samples of autistic children, their normal siblings and their parents (https://zenodo.org/record/7111193#.YzAsunbMLIU) after submitting these samples to rounds of ultracentrifugation and collecting the precipitate for proteomics analysis according to the protocol described at Andre et al (9). We considered significant Mascot scores above or close to 90 and found out that apoliproteins E (APOE) (total) and L1 (APOL1...