Gwyntwr1386 Science Journal

Hemoglobin as a biomarker for melanoma - short report Ana Pedro (1) 1. Gwyntwr1386 Pharmacy, Regus Chester Business Park, Heronsway,Chester CH4 9QR, United Kingdom anapedrolaboratories@gmail.com Introduction Anemia is a common condition within cancer patients affecting their survival (1). In cutaneous melanoma (CM), low blood hemoglobin concentration is associated with nodal involvement and metastatic disease. Although anemia in diagnosis is not an independent prognostic factor for survival in CM, it is associated with poor prognostic factors (2). Also, the interstitial fluid and the deriving lymph are in direct contact with the cellular layer of each organ. Therefore, the analysis of the composition of the lymphatic fluid may provide precise pathological biochemical and cellular information about an organ including the skin (3). For these reasons, we collected lymphatic fluid samples both from healthy patients and CM patients suffering from different stages...

Production of a portable, biodegradable flow cytometer for NHS Gwyntwr1386 Healthcare CIC ISSN 2753-8176 (online) DOI: 10.13140/RG.2.2.20918.78407 Ana Pedro1 1. Gwyntwr1386 Pharmacy, Regus Chester Business Park, Heronsway, Chester CH4 9QR, United Kingdom anapedrolaboratories@gmail.com In mammals , blood is composed by cells such as erythrocytes, leukocytes and thrombocytes and a fluid called plasma were different particles with important biological functions such as immunoglobulins, lipoproteins, or extracellular vesicles circulate (1-4). We propose the creation of a new portable, small flow cytometer composed of biodegradable and/or inert materials as possible. This new flow cytometer will be capable of analysing both cells and small particles present in blood or in other fluids and of providing a full blood cell count. This new flow cytometer (fig. 1) will be composed of a microfluidics silicone chip were is inserted a flow sheath (with sample loading point as well as wast...